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Home Remedies for Palmar-Plantar Erythrodysesthesia (Hand-Foot Syndrome)

Cool Compress

Apply a cool, damp cloth to affected areas for 10-15 minutes. Refresh the cloth as needed. It can help reduce inflammation and soothe the skin.

Coconut Oil

Gently massage a tablespoon of coconut oil onto the affected areas. Reapply 2-3 times a day or as needed for moisturization.

Epsom Salt Soak

Mix 2 cups of Epsom salt in a basin of warm water. Soak hands/feet for 15-20 minutes. Rinse with lukewarm water and pat dry. Limit the time if the skin is very sensitive.

Aloe Vera

Apply pure aloe vera gel generously to the affected areas. Reapply 2-3 times a day or as needed. Store aloe vera gel in the fridge for added cooling.

Avoid Hot Water

Use lukewarm water for bathing and washing hands. Test water temperature with a part of your body that's not affected before using.

Wear Comfortable Shoes

Opt for shoes with soft cushioning, wide toe boxes, and breathable material. Rotate footwear daily to minimize pressure points.

Cucumber Slices

Place cool cucumber slices on affected areas for 10-15 minutes. Refresh slices as needed.

Oatmeal Bath

Add 1 cup of finely ground oats to lukewarm bath water. Soak for 15-20 minutes, then rinse with lukewarm water and pat dry.

Shea Butter

Gently massage a generous amount of shea butter onto affected areas, especially after bathing. Use as often as required.

Avoid Direct Heat

Refrain from using direct heat sources. When cooking, use oven mitts or protective wear.

Vitamin E Oil

Dab a few drops of vitamin E oil onto dry areas and massage gently. Use 1-2 times daily, especially after washing hands or feet.

Lavender Essential Oil

Mix 5-6 drops of lavender oil with 1 tablespoon of a carrier oil (like coconut or jojoba oil). Gently massage onto the affected areas once or twice daily.

Urea-Based Creams

Apply as directed on the product label or as recommended by a dermatologist. It's crucial to choose creams suited for the severity of the condition.

Witch Hazel

Dampen a soft cloth with witch hazel and gently dab onto the affected areas. Let it air dry. Do not rinse. Repeat 1-2 times a day.

Gentle Skincare Products

Opt for soaps and lotions labeled "for sensitive skin" or "fragrance-free". Always patch-test a new product on a small area before full application.

Jojoba Oil

Massage a few drops of jojoba oil onto affected areas, especially after exposure to water. Can be used multiple times a day as needed.

Chamomile Compress

Brew a strong chamomile tea (2-3 tea bags in a cup of boiling water), let it cool, and use it as a compress on affected areas for 10-15 minutes. Refresh the compress as needed.

Elevate Affected Limbs

When resting, elevate hands or feet on pillows to help reduce swelling and discomfort. Try to elevate for at least 30 minutes, 2-3 times a day.

Hyaluronic Acid Serum

Apply a thin layer to affected areas, especially after washing. Follow up with a moisturizer to lock in hydration. Consult the product's instructions for exact quantities.

Cotton Gloves & Socks

After applying a moisturizer or treatment, wear cotton gloves or socks to help retain moisture. It's especially effective when worn overnight.

The information on this site is not meant to diagnose or treat any illness. Always consult a doctor before making health decisions. This content is for educational purposes only and should not replace professional medical advice.

Home remedies for other side effects

Changes in hair texture or color
Kidney issues (renal toxicity)
Loss of smell
Infection risk
Hearing changes (tinnitus, hearing loss)
Skin irritation or rash
Muscle cramps
Menopausal symptoms (for women)
Weight loss

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