Targeted Therapy

  • 1. What is Targeted therapy?
  • Targeted therapy Targeted therapy is a type of Cancer Treatment that uses drugs designed to “target” cancer cells without affecting normal cells. Cancer cells typically have changes in their genes that make them different from normal cells. Genes are part of a cell’s DNA that tell the...
  • 2. How is it Different From Chemotherapy?
  • Targeted therapy drugs, like other drugs used to treat cancer, are technically considered Chemotherapy. But Targeted therapy drugs don’t work the same way as traditional or standard Chemotherapy (chemo) drugs. Targeted drugs zero in on some of the changes that make cancer cells different fro...
  • 3. How Targeted Therapy Works
  • Targeted therapies are made to find and attack specific areas or substances in cancer cells, or can detect and block certain kinds of messages sent inside a cancer cell that tell it to grow. Some of the substances in cancer cells that become the “targets” of targeted therapies are: Too much ...
  • 4. Targeted Therapy as Precision Medicine
  • Targeted therapy is sometimes called precision medicine or personalized medicine. This is because they are made to exactly target specific changes or substances in cancer cells, and these targets can be different even when people have the same type of cancer. Certain types of tumors are tested f...
  • 5. Types of Targeted Therapy
  • Many kinds of cancer can be treated with targeted therapies, and there are many different types of targeted therapies. Here are some types with a few examples of how they are used. Angiogenesis inhibitors: These block the formation of new blood vessels that feed and nourish the cancer cells. Ex...
  • 6. References
  • Alessandrini L, Perin T, Kadare S, et al. Cancer Targeted therapy strategy: The pathologist’s perspectives. Curr Cancer Drug Targets.2018; 18(5):410-420.American Society of Clinical Oncology (ASCO). Understanding targeted therapy. Accessed at https://www.cancer.net/navigating-cancer-care/how-...