Immunotherapy

  • 1. What is Immunotherapy in Cancer?
  • Immunotherapy is a type of treatment that uses the body’s own immune system to recognize and kill cancer cells. Cancer cells often can fool the body into not recognizing they are dangerous. If the body can’t tell the difference between cancer cells and healthy cells, cancer cells may be able to...
  • 2. Why is Immunotherapy Needed?
  • Immunotherapy has the potential to achieve durable clinical responses in some patients. In addition, an improved quality of life may also make Immunotherapy an attractive choice for people who have this treatment option. Immunotherapy may be an option for patients to consider because the side e...
  • 3. How is Immunotherapy Given?
  • Different forms of Immunotherapy may be given in different ways. These include: Intravenous (IV): The Immunotherapy goes directly into a vein.Oral: The Immunotherapy comes in pills or capsules that you swallow.Topical: The Immunotherapy comes in a cream that you rub onto your skin. Th...
  • 4. Immunotherapy Work Against Cancer
  • As part of its normal function, the immune system detects and destroys abnormal cells and most likely prevents or curbs the growth of many cancers. For instance, immune cells are sometimes found in and around tumors. These cells, called tumor-infiltrating lymphocytes or TILs, are a sign that the im...
  • 5. Side Effects of Immunotherapy
  • Immunotherapy can cause side effects, many of which happen when the immune system that has been revved-up to act against the cancer also acts against healthy cells and tissues in the body. Different people have different side effects. The ones you have and how they make you feel will depend on how ...
  • 6. Types of Immunotherapy
  • What are the types of Immunotherapy? Monoclonal antibodies (mABs) Monoclonal antibodies are laboratory produced antibodies designed to recognise and bind to specific receptors found on the surface of cells. They are derived from natural antibodies, complex proteins derived from a single B cel...
  • 7. Cancer vaccines, Cytokine therapies, Interferon & Aldesleukin
  • Vaccines to treat cancer Vaccines are a type of Immunotherapy. Research in this area is at an early stage and vaccines are mainly available as part of clinical trials. What vaccines are? Normally, vaccines help to protect us from disease. They are made from weakened or harmless versions o...
  • 8. Adoptive T-cell Transfer
  • CAR T-cell therapy CAR T-cell therapy is a type of Immunotherapy. You might also hear it called a type of adoptive cell transfer.CAR T-cell therapy is a very complex and specialist treatment. With this treatment, a specialist collects and makes a small change to your T cells. These then target ...
  • 9. What is Radioimmunotherapy
  • Radioimmunotherapy (RIT) involves a small amount of radioactive material (radionuclide) — that is combined with a molecule engineered in a laboratory (monoclonal antibody). This monoclonal antibody-radionuclide compound is called a radiopharmaceutical. Monoclonal antibodies are able to recognize ...
  • 10. What conditions are treated with radioimmunotherapy?
  • There are two RIT agents approved by the U.S. Food and Drug Administration (FDA): Zevalin and Bexxar. Both of these are used to treat patients with B-cell Follicular non-Hodgkin Lymphoma (NHL) that has not responded to Chemotherapy treatment, although these can be used in some other types of ly...
  • 11. Advantages of Radioimmunotherapy
  • RIT offers more personalized Cancer Treatment because radiopharmaceuticals can be tailored to the unique biologic characteristics of the patient‘s tumor, are highly selective in their ability to adhere to cancer cells, and can limit radiation exposure to healthy tissue. As a result, RIT has ...
  • 12. Special Considerations
  • The medical facility where the RIT treatment is performed will provide you with instructions for special care to be taken at home, including important steps to take immediately afterwards, and in the days and week following treatment. These instructions can vary between different facilities, and yo...