Book Appointment with Dr Daxesh Patel in Ahmedabad

Dr Daxesh Patel

Surgical Oncologist

14 Years Exp. Ahmedabad

Head And Neck Cancer

HCG Cancer Centre, Ahmedabad

14 years of experience

MBBS, MS, MCh

About Dr Daxesh Patel:

Dr Daxesh Patel is part of the Head & Neck Oncology team at HCG Cancer Center, Ahmedabad. After completing MBBS and MS (ENT) from a Medical College in Baroda, he pursued MCh in Head & Neck Cancer Surgery at a famous Institute in Kochi. Thereafter, to gain further experience in the field of Head & Neck Oncology, he went to one of the topmost cancer centers of the world- Memorial Sloan Kettering Cancer Center, New York, USA, for 2 years, where, apart from clinical academic activities, he was actively involved in research related to tobacco induced oral cavity cancer and different modalities to prevent it. Dr Daxesh has special interest in treating cancers involving base of skull, tobacco induced oral cavity and laryngeal cancers, minimally invasive laryngeal surgery through LASER etc. He is also keen on rehabilitating patients after cancer ablative surgery, through plastic & reconstructive surgery, and speech and swallowing therapy and voice restoration after laryngectomy. He has published many clinical and basic science research papers in international peer reviewed journals and has won many awards, including a gold medal at a national level forum on Head & Neck cancer. He has been invited as speaker and as panelist at various conferences and is a key member in the web management committee of the Foundation for Head & Neck Oncology, India.

Education:

MBBS, Baroda Medical College, Vadodara, India MS (ENT), Baroda Medical College, Vadodara, India M.Ch (Head & Neck Oncology), Amrita Institute of Medical Sciences, Kochi, India

Experience:

Head Neck Cancer Surgeon at HCG Cancer Center, Sola, Ahmedabad Visiting Investigator at Memorial Sloan Kettering Cancer Center

Memberships:

Aastha Oncology Associates

Areas of interest:

Head And Neck Cancer, Lip and Oral Cavity Cancer, Laryngeal Cancer .

Research publications:

Patel, Daxesh & Nair, Sneha & Suhagia, Bhanubhai & Patel, Bhargav. (2016). A novel, sensitive and selective method of UPLC/MS-MS for rapid simultaneous determination of Midodrine and its active metabolite Desglymidodrine in human plasma: Application to support bioequivalence study in healthy Human volunteers.. Journal of Pharmaceutical and Biomedical Analysis. 131. https://doi.org/10.1016/j.jpba.2016.09.005 Nair, Sneha & Patel, Daxesh & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2016). Simultaneous analysis of glucocorticosteroid fluticasone propionate and its metabolite fluticasone propionate 17_-carboxylic acid in human plasma by UPLCРMS/MS at sub pg/mL level. Journal of Pharmaceutical and Biomedical Analysis. 135. https://doi.org/10.1016/j.jpba.2016.12.008 Patel, Daxesh & Krausz, Kristopher & Xie, Cen & Beyoglu, Diren & Gonzalez, Frank & Idle, Jeffrey. (2017). Metabolic profiling by gas chromatography-mass spectrometry of energy metabolism in high-fat diet-fed obese mice. PLoS ONE. 12. https://doi.org/10.1371/journal.pone.0177953 Chaudhary, Darshan & Patel, Daxesh & Shah, Jaivik & Shah, Priyanka & Patel, Vijay & S, Shrivastav. (2017). Analysis of Amoxicillin and Clavulanic Acid by UPLC-MS/MS in Human Plasma for Pharmacokinetic Application. Journal of Modern Drug Discovery and Drug Delivery Research. 2. 1-10. https://doi.org/10.15297/JMDDR.V2I3.01 Li, Guolin & Xie, Cen & Lu, Siyu & Nichols, Robert & Tian, Yuan & Li, Licen & Patel, Daxesh & Ma, Yinyan & Brocker, Chad & Yan, Tingting & Krausz, Kristopher & Xiang, Rong & Gavrilova, Oksana & Patterson, Andrew & Gonzalez, Frank. (2017). Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Cell Metabolism. 26. https://doi.org/10.1016/j.cmet.2017.08.019 Nair, Sneha & Patel, Daxesh & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2017). Ultra performance liquid chromatography-tandem mass spectrometry assay for determination of plasma nomegestrol acetate and estradiol in healthy postmenopausal women. Biomedical Chromatography. 32. e4086. https://doi.org/10.1002/bmc.4086 Li, Guolin & Xie, Cen & Lu, Siyu & Nichols, Robert & Tian, Yuan & Li, Licen & Patel, Daxesh & Ma, Yinyan & Brocker, Chad & Yan, Tingting & Krausz, Kristopher & Xiang, Rong & Gavrilova, Oksana & Patterson, Andrew & Gonzalez, Frank. (2017). Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Cell Metabolism. 26. 801. https://doi.org/10.1016/j.cmet.2017.10.007 Patel, Chirag & Kumar, Prasanth & Pandya, Himanshu & Modi, Krunal & Patel, Daxesh & Gonzalez, Frank. (2017). Retrieval of promiscuous natural compounds using multiple targets docking strategy: A case study on kinase polypharmacology. Bioinformatics and Biomedicine (BIBM). 288-291. https://doi.org/10.1109/BIBM.2017.8217665 Nair, Sneha & Patel, Daxesh & Gonzalez, Frank & Patel, Bhargav & Singhal, Puran & Chaudhary, Darshan. (2017). Simultaneous determination of etonogestrel and ethinyl estradiol in human plasma by UPLC-MS/MS and its pharmacokinetic study. Biomedical Chromatography. 32. e4165. https://doi.org/10.1002/bmc.4165 Nair, Sneha & Patel, Daxesh & Gonzalez, Frank & Singhal, Puran & Chaudhary, Darshan. (2018). Analysis of Levonorgestrel in Human Plasma by UPLC - MS/MS: Application to a Bioequivalence Study in Healthy Volunteers. JOURNAL OF ADVANCEMENT IN MEDICAL AND LIFE SCIENCES. https://doi.org/10.5281/zenodo.1162427 Manza, Jawansing & Maisuria, Rushabh & Chaudhari, Devendra & Dave, Divyang & Gajra, Yatin & Patel, Daxesh. (2018). Comparative study between cyanoacrylate tissue adhesive versus skin sutures in closure of wound in 60 operated cases of open inguinal hernia. International Surgery Journal. 5. 1908. https://doi.org/10.18203/2349-2902.isj20181608 Moreno Marin, Nuria & Merino, Jaime M. & Alvarez, Alberto & Patel, Daxesh & Takahashi, Shogo & Gonz‡lez-Sancho, JosЋ & Gandolfo, Pablo & Rios, Rosa & Mu–oz, Alberto & Gonzalez, Frank & Fernandez-Salguero, Pedro. (2018). Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK and Wnt/_-Catenin Signaling. iScience. 4. https://doi.org/10.1016/j.isci.2018.05.006 Brocker, Chad & Patel, Daxesh & Velenosi, Thomas & Kim, Donghwan & Yan, Tingting & Yue, Jiang & Li, Guolin & Krausz, Kristopher & Gonzalez, Frank. (2018). Extrahepatic PPAR_ modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice. Journal of Lipid Research. 59. jlr.M088419. https://doi.org/10.1194/jlr.M088419 Zhao, Jie & Xie, Cen & Mu, Xiyan & Krausz, Kristopher & Patel, Daxesh & Shi, Xiaowei & Gao, Xiaoxia & Wang, Qiao & Gonzalez, Frank. (2018). Metabolic alterations in triptolide_induced acute hepatotoxicity. Biomedical Chromatography. 32. e4383. https://doi.org/10.1002/bmc.4383 Patel, Chirag & John. J, Georrge & Modi, Krunal & Narechania, Moksha & Patel, Daxesh & Gonzalez, Frank & Pandya, Himanshu. (2018). Pharmacophore-based virtual screening of catechol-o-methyltransferase (COMT) inhibitors to combat Alzheimer's disease. Journal of biomolecular Structure & Dynamics. 36. 3938Р3957. https://doi.org/10.1080/07391102.2017.1404931 Patel, Daxesh & Yan, Tingting & Kim, Donghwan & Dias, Henrique & Krausz, Kristopher & Kimura, Shioko & Gonzalez, Frank & Cresino, Alyssa. (2019). Withaferin A Improves Nonalcoholic Steatohepatitis in Mice. Journal of Pharmacology and Experimental Therapeutics. 371. https://doi.org/10.1124/jpet.119.256792 Wang, Xiaoxin & Takahashi, Shogo & Libby, Andrew & Myakala, Komuraiah & Jones, Bryce & Bhasin, Kanchan & Qi, Yue & Krausz, Kristopher & Zerfas, Patricia & Panov, Julia & velenosi, thomas & Patel, Daxesh & Da, Parnaz & Ginley, Brandon & Sarder, Pinaki & Titievsky, Avi & Sharov, Vadim & Ostretsov, Boris & Kopp, Jeffrey & Levi, Moshe. (2019). ERR agonism reverses mitochondrial dysfunction and inflammation in aging. https://doi.org/10.1101/755801 Patel, Chirag & Kumar, Prasanth & Rawal, Rakesh & Patel, Daxesh & Gonzalez, Frank & Pandya, Himanshu. (2019). A multiparametric organ toxicity predictor for drug discovery. Toxicology mechanisms and methods. 30. https://doi.org/10.1080/15376516.2019.1681044 Patel, Chirag & Jaiswal, Dharmesh & Jani, Siddhi & Patel, Daxesh & Gonzalez, Frank & Pandya, Himanshu. (2020). Molecular Interaction Studies of Natural Compounds against Coronavirus Hemagglutinin-Esterase in complex with ACE2 receptor: An In Silico Approach. https://doi.org/10.22541/au.159242063.36465517 Patel, Daxesh & Pauly, Gary & Tada, Takeshi & Parker, Amelia & Toulabi, Leila & Kanke, Yasuyuki & Oike, Takahiro & Krausz, Kristopher & Gonzalez, Frank & Harris, Curtis. (2020). Improved detection and precise relative quantification of the urinary cancer metabolite biomarkers Р Creatine riboside, creatinine riboside, creatine and creatinine by UPLC-ESI-MS/MS: Application to the NCI-Maryland cohort population controls and lung cancer cases. Journal of pharmaceutical and biomedical analysis. https://doi.org/10.1016/j.jpba.2020.113596 Sharma, Primal & Soni, Kanchan & Guttikar, Swati & Singhal, Puran & Patel, Daxesh & S, Shrivastav. (2012). Separation of all-trans- and 13-cis-isomers of acitretin on a reversed-phase column, optimization of stability conditions and their simultaneous quantitation in human plasma by liquid chromatography-tandem mass spectrometry. Anal. Methods. 4. 791-806. https://doi.org/10.1039/C2AY05852A Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2012). Challenges in the simultaneous quantitation of sumatriptan and naproxen in human plasma: Application to a bioequivalence study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 902. 122-31. https://doi.org/10.1016/j.jchromb.2012.06.041 Sharma, Primal & Guttikar, Swati & Solanki, Gajendrasinh & Patel, Daxesh & S, Shrivastav. (2012). Determination of (S)-(+)- and (R)-(-)-ibuprofen enantiomers in human plasma after chiral precolumn derivatization by reversed-phase LC-ESI-MS/MS. Bioanalysis. 4. 2909-27. https://doi.org/10.4155/bio.12.275 Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2012). Highly sensitive and rapid ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of nifedipine in human plasma and its application to a bioequivalence study. Biomedical chromatography : BMC. 26. 1509-18. https://doi.org/10.1002/bmc.2725 Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2013). Reliable and Precise Determination of Montelukast in Human Plasma by UPLC-MS/MS. Open Journal of Analytical Chemistry Research. 1. 59. https://doi.org/10.12966/ojacr.11.03.2013 Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2013). UPLC-MS/MS assay for the simultaneous quantification of carvedilol and its active metabolite 4-hydroxyphenyl carvedilol in human plasma to support a bioequivalence study in healthy volunteers. Biomedical chromatography : BMC. 27. https://doi.org/10.1002/bmc.2889 Sharma, Primal & Patel, Daxesh & Sanyal, Mallika & Berawala, Hiren & Guttikar, Swati & S, Shrivastav. (2013). Simultaneous analysis of oxybutynin and its active metabolite N-desethyl oxybutynin in human plasma by stable isotope dilution LC-MS/MS to support a bioequivalence study. Journal of pharmaceutical and biomedical analysis. 84C. 244-255. https://doi.org/10.1016/j.jpba.2013.06.024 Sharma, Primal & Patel, Daxesh & Sanyal, Mallika & Berawala, Hiren & Guttikar, Swati & S, Shrivastav. (2013). Simultaneous analysis of oxybutynin and its active metabolite N-desethyl oxybutynin in human plasma by stable isotope dilution LC-MS/MS to support a bioequivalence study. Journal of pharmaceutical and biomedical analysis. 84C. 244-255. https://doi.org/10.1016/j.jpba.2013.06.024 Patel, Daxesh & Sharma, Primal & Patel, Bhargav & Sanyal, Mallika & Singhal, Puran & S, Shrivastav. (2013). Analysis of 21-hydroxy deflazacort in human plasma by UPLCРMS/MS: Application to a bioequivalence study in healthy volunteers. Journal of pharmaceutical and biomedical analysis. 85C. 213-217. https://doi.org/10.1016/j.jpba.2013.07.035 Sharma, Primal & Patel, Daxesh & Sanyal, Mallika & Guttikar, Swati & S, Shrivastav. (2013). Parallel achiral-chiral determination of oxybutynin, N-desethyl oxybutynin and their enantiomers in human plasma by LC-MS/MS to support a bioequivalence trial. Journal of pharmaceutical and biomedical analysis. 88C. 81-91. https://doi.org/10.1016/j.jpba.2013.08.032 Shah, Jaivik & Shah, Priyanka & Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & S, Shrivastav. (2014). Highly Sensitive Determination of Colchicine in Human Plasma by UPLC-MS/MS for a Clinical Study in Healthy Subjects. American Journal of Modern Chromatography. 1. 67-83. https://doi.org/10.7726/ajmc.2014.1006 Sharma, Primal & Contractor, Pritesh & Guttikar, Swati & Patel, Daxesh & S, Shrivastav. (2014). Development of a sensitive and rapid method for quantitation of (S)-(_)- and (R)-(+)-metoprolol in human plasma by chiral LCРESIРMS/MS. Journal of Pharmaceutical Analysis. 4. 63Р79. https://doi.org/10.1016/j.jpha.2013.02.008 Bhatt, Nejal & Chavada, Vijay & Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & S, Shrivastav. (2014). Determination of cilostazol and its active metabolite 3,4-dehydro cilostazol from small plasma volume by UPLC-MS/MS. Journal of Pharmaceutical Analysis. 5. https://doi.org/10.1016/j.jpha.2014.08.001 Bhatt, Nejal & Chavada, Vijay & Patel, Daxesh & Sharma, Primal & Sanyal, Mallika & S, Shrivastav. (2014). Determination of cilostazol and its active metabolite 3,4-dehydro cilostazol from small plasma volume by UPLC-MS/MS. Journal of Pharmaceutical Analysis. 5. https://doi.org/10.1016/j.jpha.2014.08.001 Chaudhary, Darshan & Patel, Daxesh & Shah, Jaivik & Shah, Priyanka & Sanyal, Mallika & S, Shrivastav. (2015). Application of a UPLC-MS/MS method for the analysis of alosetron in human plasma to support a bioequivalence study in healthy males and females. Biomedical chromatography : BMC. 29. https://doi.org/10.1002/bmc.3454 Shah, Jaivik & Patel, Daxesh & Shah, Priyanka & Sanyal, Mallika & S, Shrivastav. (2015). Simultaneous quantification of atenolol and chlorthalidone in human plasma by ultra performance liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC. 30. https://doi.org/10.1002/bmc.3537 Chaudhary, Darshan & Patel, Daxesh & Shah, Priyanka & Shah, Jaivik & Sanyal, Mallika & S, Shrivastav. (2015). Determination of lercanidipine in Human plasma by an improved UPLC-MS/MS method for a bioequivalence study. Journal of Pharmaceutical Analysis. 6. https://doi.org/10.1016/j.jpha.2015.09.001