Free Cancer Report

Know Your Cancer

Curcumin and its vitality for treating cancer

Curcumin is extracted from turmeric. Turmeric is well-known for its nutritious value in the industry of medicine. Curcumin comes with a myriad of health-promoting components, specifically calming and reducing inflammation. Curcumin cannot be directly consumed and absorbed by the body. Nonetheless, mixing it with fats and pepper can substantially enhance the absorption levels. Many experts suggest that Curcumin should be consumed in an empty stomach. One should consult their doctor to understand the amount and duration of consuming this medication.

A few instances of Curcumin

  • Many Curcumin derivatives are being produced to enhance the absorption rate. Many promising laboratory results back this statement.
  • Curcumin is sometimes in the form of liposomal, where pure Curcumin is relatively extracted and positioned in a lipid layered bubble, thereby taking the shape of a cell wall. Studies performed on these liposomal Curcumin extracts show efficient tumor growth-mitigating effect, along with driving apoptosis related to cancer cells.
  • Nanoformulations found in Colorectal Cancer treatment aim to improve water solubility, efficacy, and delivery.
  • A study conducted in 2016 suggests that about 40% Curcumin and guar gum formulation offered a productive secretion into the colon directly.
  • The distinctive metrics formulation has comparatively enhanced oral absorption and metabolization to a likely derivative.

Curcumin and Cancer

Curcumin plays a vital role in combating cancer cells. It relatively mitigates the spread or expansion of cancer cells and enhances the patient's survival rate. It also combines with cancer treatments like Chemotherapy and Radiotherapy to substantially improve the anti-cancer effect.

Anti-cancer effects

There are a multitude of research pieces that suggest the anti-cancer properties of Curcumin. Although further research is required, it is clear that Curcumin can effectively mitigate cell proliferation, thereby enhancing cell cycle arrest, senescence, and apoptosis. Curcumin is a proven medication in the decreased expression of a plethora of transcription factors, enzymes, growth factors, different cell-signalling elements, and inflammatory cytokines related to cancer progression.

Clinical Evidence

There is limited clinical evidence that suggests the exact and accurate effects of Curcumin on cancer. Several studies have proven that Curcumin helps in the treatment of Colorectal Cancer. A few other clinical trials conducted amongst humans suggest that Curcumin offers limited anti-cancer effects. Their effectiveness depends individually based on the patient to patient.

Curcumin lowered the disease markers in various studies. It showed positive results in prostate cancer, multiple myeloma, pancreatic cancer, and cervical neoplasia. In colorectal cancer, it enhanced the apoptotic cells relatively. It also showed a prominent response to Tumor Markers.

Different cancers and their lab evidence

  • Colorectal Cancer

In colorectal cancer, a safe and efficient dose of a Curcumin supplement promoted colorectal liver metastases in many patients. It offers antitumor properties, along with several anticancer effects including, anti-angiogenic. Furthermore, it finished the number and volume of animal Tumors, promoted cell self-clearing, suppressed metastasis and angiogenesis, decreased multidrug dose-limiting toxicity and resistance, and balanced and relieved tumors for treatments like Chemotherapy and Radiation therapy.

  • Breast Cancer

Curcumin showed several effects on Breast Cancer starting from suppressing the tumor metastasis and expansion, induced cell apoptosis on being used as an adjunct therapy, improved oxaliplatin toxicity in the primary malignant cells, detected regressed tumor growth, and released tumor Pain and inflammation caused by treatments like Chemotherapy and Radiotherapy.

  • Prostate Cancer

In prostate cancer, Curcumin lowered cell proliferation, enhanced cell apoptosis, suppressed stem cell proliferation, reduced angiogenesis, and mitigated the process of bone metastatic in both androgen-independent and androgen-sensitive Prostate Cancer cells.

  • Ovarian Cancer

Curcumin showed limited anti-cancer effects on ovarian cancer. A few of them include enhanced sensitivity to cisplatin when utilized with quercetin, induced cell apoptosis, and other synergistic anticancer effects when combined with dihydroartemisinin.

  • Additional

Along with the effects mentioned above, curcumin, when combined with 5-fluorouracil, mitigated the cancer growth in gastric carcinoma, and also worked on cancers related to stomach, cervical, colorectal, head, uterine, neck, lung, oral, esophagus, pancreas, and bone.

Furthermore, it was also efficacious in chemosensitization and Radiotherapy sensitization.

Curcumin in promoting wellness and mitigating side-effects

Limited trials conducted on Curcumin suggest its vitality for inhibiting several side effects and enhancing the way mitt of life.

  • Curcumin mitigated an array of side effects caused by excruciatingly painful cancer treatments, including Radiotherapy and Chemotherapy. It, moreover, helped in protecting the human liver.
  • Curcumin relatively lowered the criticality of Breast Cancer radiation dermatitis. However, more studies are required to understand this in-depth.
  • A study was conducted among 160 cancer patients encountering cancer treatments like Radiotherapy and Chemotherapy. The study examined if or whether a reliable dose of Curcumin lowered symptoms like fatigue, nausea, diarrhea, loss of appetite, insomnia, and much more, it was recorded that most of these symptoms were comparatively relived in consuming Curcumin supplements.
  • Other severe symptoms related to Prostate Cancer were much milder on consuming Curcumin.
  • Curcumin also lowered Depression levels in non-cancer patients.
  • It enhanced body weight in several Colorectal Cancer patients undergoing cancer diagnosis.
  • It decreased cholesterol levels in numerous patients prone to developing cardiovascular diseases.
  • Curcumin enhanced the quality of life in patients with critical tumors.
  • Mitigated the risk of cachexia in patients suffering from Colorectal Cancer.

Cautions

Curcumin is certified as a secure supplement by the FDA. Several clinical trials have made use of up to 12 grams of Curcumin per day. Nonetheless, specific constituents in Curcumin can combine with iron, thereby lowering iron's potentiality. This can be dangerous for people with iron deficiencies. It is highly recommended that you consult your doctor before making use of Curcumin for medical purposes.