Curcumin is extracted from turmeric. Turmeric is well-known for its nutritious value in the industry of medicine. Curcumin comes with a myriad of health-promoting components, specifically calming and reducing inflammation. Curcumin cannot be directly consumed and absorbed by the body. Nonetheless, mixing it with fats and pepper can substantially enhance the absorption levels. Many experts suggest that Curcumin should be consumed in an empty stomach. One should consult their doctor to understand the amount and duration of consuming this medication.
Curcumin plays a vital role in combating cancer cells. It relatively mitigates the spread or expansion of cancer cells and enhances the patient's survival rate. It also combines with cancer treatments like Chemotherapy and Radiotherapy to substantially improve the anti-cancer effect.
There are a multitude of research pieces that suggest the anti-cancer properties of Curcumin. Although further research is required, it is clear that Curcumin can effectively mitigate cell proliferation, thereby enhancing cell cycle arrest, senescence, and apoptosis. Curcumin is a proven medication in the decreased expression of a plethora of transcription factors, enzymes, growth factors, different cell-signalling elements, and inflammatory cytokines related to cancer progression.
There is limited clinical evidence that suggests the exact and accurate effects of Curcumin on cancer. Several studies have proven that Curcumin helps in the treatment of Colorectal Cancer. A few other clinical trials conducted amongst humans suggest that Curcumin offers limited anti-cancer effects. Their effectiveness depends individually based on the patient to patient.
Curcumin lowered the disease markers in various studies. It showed positive results in prostate cancer, multiple myeloma, pancreatic cancer, and cervical neoplasia. In colorectal cancer, it enhanced the apoptotic cells relatively. It also showed a prominent response to Tumor Markers.
In colorectal cancer, a safe and efficient dose of a Curcumin supplement promoted colorectal liver metastases in many patients. It offers antitumor properties, along with several anticancer effects including, anti-angiogenic. Furthermore, it finished the number and volume of animal Tumors, promoted cell self-clearing, suppressed metastasis and angiogenesis, decreased multidrug dose-limiting toxicity and resistance, and balanced and relieved tumors for treatments like Chemotherapy and Radiation therapy.
Curcumin showed several effects on Breast Cancer starting from suppressing the tumor metastasis and expansion, induced cell apoptosis on being used as an adjunct therapy, improved oxaliplatin toxicity in the primary malignant cells, detected regressed tumor growth, and released tumor Pain and inflammation caused by treatments like Chemotherapy and Radiotherapy.
In prostate cancer, Curcumin lowered cell proliferation, enhanced cell apoptosis, suppressed stem cell proliferation, reduced angiogenesis, and mitigated the process of bone metastatic in both androgen-independent and androgen-sensitive Prostate Cancer cells.
Curcumin showed limited anti-cancer effects on ovarian cancer. A few of them include enhanced sensitivity to cisplatin when utilized with quercetin, induced cell apoptosis, and other synergistic anticancer effects when combined with dihydroartemisinin.
Along with the effects mentioned above, curcumin, when combined with 5-fluorouracil, mitigated the cancer growth in gastric carcinoma, and also worked on cancers related to stomach, cervical, colorectal, head, uterine, neck, lung, oral, esophagus, pancreas, and bone.
Furthermore, it was also efficacious in chemosensitization and Radiotherapy sensitization.
Limited trials conducted on Curcumin suggest its vitality for inhibiting several side effects and enhancing the way mitt of life.
Curcumin is certified as a secure supplement by the FDA. Several clinical trials have made use of up to 12 grams of Curcumin per day. Nonetheless, specific constituents in Curcumin can combine with iron, thereby lowering iron's potentiality. This can be dangerous for people with iron deficiencies. It is highly recommended that you consult your doctor before making use of Curcumin for medical purposes.