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What is Sancuso?

What is Sancuso?

Sancuso (granisetron) blocks the actions of chemicals in the body that may cause nausea and vomiting.

Sancuso skin patches are used to prevent nausea and vomitting caused by cancer chemotherapy.

Sancuso may also be used for purposes not listed in this medication guide.

Warnings for Sancuso

Before using Sancuso, tell your doctor if you have a stomach or intestinal disorder, if you have recently had stomach or intestinal surgery, or if you have ever had an allergic reaction to any type of medicated skin patch. You may need a dose adjustment or special tests to safely use Sancuso.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Avoid exposing the skin patch or your upper arm to sunlight, sunlamps, or tanning beds. Natural or artificial sunlight can cause a skin reaction where the Sancuso skin patch is worn. This effect may last for up to 10 days after the patch is removed. Wear protective clothing over your arms while you are wearing the skin patch and for at least 10 days after you remove a patch. Do not use Sancuso during a time when you are not having chemotherapy, unless your doctor has told you to.

Before taking this medicine

You should not use Sancuso if you are allergic to granisetron.

To make sure Sancuso is safe for you, tell your doctor if you have:

  • a stomach or intestinal disorder;
  • if you have recently had stomach or intestinal surgery; or
  • if you have ever had an allergic reaction to any type of medicated skin patch.

Sancuso is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether granisetron passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Sancuso?

The Sancuso skin patch is usually applied at least 24 to 48 hours before the start of your chemotherapy. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Apply the Sancuso patch to clean, dry, and hairless skin on the outer part of your upper arm. Avoid placing the patch on skin that is red, irritated, or damaged. Press the patch firmly into place and make sure it is well sealed around the edges.

Leave the patch in place during your chemotherapy treatment, and for at least 24 hours after your treatment has ended. Peel off the patch gently when removing it.

You may continue wearing a Sancuso skin patch for up to 7 days if needed, depending on your chemotherapy schedule. Follow your doctor’s dosing instructions very carefully.

Choose a different place on your body to wear the patch each time you put on a new one. Do not use the same skin area twice within 7 days.

Do not wear more than one Sancuso patch at a time. 

Using extra skin patches will not make the medicine more effective. Never cut a skin patch.

If a patch falls off, try sticking it back into place. If it does not stick well, put on a new patch and leave it on only for the rest of your wearing time. Do not change your patch removal schedule.

After removing a patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

Sancuso is not likely to be useful if you keep using it during times when you are not receiving chemotherapy.

Do not share this medicine with another person.

Keep each patch in its foil pouch until you are ready to use it. Store the pouches in their original container at room temperature, away from moisture and heat.


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