What is Chronic Myelogenous Leukemia (CML)

Overview: 

Chronic myelogenous leukemia (CML) is a rare type of bone marrow cancer that affects the spongy tissue inside bones that produces blood cells. The number of white blood cells in the blood increases as a result of CML. The name “chronic” refers to the fact that chronic myelogenous leukemia progresses more slowly than acute forms of leukemia. In chronic myelogenous leukemia, the term “myelogenous” refers to the type of cells afflicted by cancer. Chronic myeloid leukemia and chronic granulocytic leukemia are other names for chronic myelogenous leukemia. It mostly affects older persons and rather rarely affects youngsters, while it can strike anyone at any age.

People with chronic myelogenous leukemia now have a much better prognosis thanks to advances in treatment. After diagnosis, the majority of persons will go into remission and survive for many years.

Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is a kind of leukemia that affects white blood cells. It’s a sort of cancer that begins in the bone marrow’s blood-forming cells. An early (immature) version of myeloid cells — the cells that make red blood cells, platelets, and most types of white blood cells — undergoes a genetic alteration in CML (except lymphocytes). This mutation results in the formation of an aberrant gene known as BCR-ABL, which transforms the cell into a CML cell. Leukemia cells multiply and multiply in the bone marrow, eventually spilling into the bloodstream. Cells can settle in other regions of the body, including the spleen, over time.

CML is slow-growing leukemia that can quickly deteriorate into difficult-to-treat acute leukemia.

CML mainly affects adults, although it can also affect children on rare occasions. In general, they are treated similarly to adults.

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