Melatonin is a product that is regulated by the FDA as a dietary supplement. It is only given at prescribed conditions for safety or effectiveness. It may cause drowsiness. Patients should not work on any heavy equipment until familiar with its effects. It has only been accepted as a supplementary form of treatment during cancer treatments, as the hormone is believed to be a cell-protector, involved in antioxidative processes and immunomodulation.

In conclusion, Melatonin may have multiple effects and plays a vital role in the apoptosis of cells. For research purposes, the biomodulation of cancer treatments by using Melatonin can confirm a reduction in toxicity and an increase in the efficacy of Chemotherapy on patients.