Latest research on Liver Cancer

Liver Cancer Research

Doctors are working to understand more about liver cancer, including how to avoid it, how to treat it, and how to care for patients who have been diagnosed with it. Clinical trials may provide new alternatives for patients in the following research areas. Always consult your doctor to determine the most appropriate diagnostic and treatment choices for you.

  • Vaccines against cancer: Cancer vaccines are drugs that can aid the immune system in recognizing and attacking HCC cells. An immune system stimulant, such as sargramostim, is sometimes added to the vaccine (Leukine, Prokine).
  • Taking multiple systemic cancer drugs simultaneously: Different medications work in different ways to kill cancer cells. Combining medications can improve the likelihood of more cancer cells being destroyed. Frequently, one medicine will aid the effectiveness of another. 
  • The use of many therapies: Researchers are investigating if combining therapies like RFA and chemoembolization is more beneficial than doing it separately.
  • Anti-angiogenesis drugs: They are medications that inhibit the growth of new blood vessels. Several different anti-angiogenic medications are being examined in clinical trials, in addition to sorafenib and regorafenib.
  • Transplantation of the liver: It is being used more frequently. Researchers are investigating increasing the criteria for liver transplantation for HCC. More patients would be eligible for the surgery as a result of this.
  • Gene therapy: It is a type of genetic therapy that involves fighting cancer; this new medicine alters a gene. Even though gene therapy is still in its early phases of development, certain clinical trials have already begun. In one case, the new gene improves the effectiveness of chemotherapy. A gene can be directly delivered into the tumour in this treatment. The doctor then administers an inactive medicine to the patient, and the new gene aids in activating the drug in the tumour. This strategy is also being investigated in conjunction with the other aforementioned medicines.
  • Supportive care/palliative care: Clinical trials are currently being conducted to find better ways to reduce the symptoms and side effects of current HCC treatments to improve patient comfort and quality of life.