Latest Research on Gestational Trophoblastic Disease

Executive Summary

Several latest research studies have been conducted to seek more information on the gestational trophoblastic disease, related prevention methods, diagnostic process at the initial phase, and best treatment strategies. Clinical trials are being conducted for people with different tumors, particularly other gynecologic tumors, including GTD. Researchers are studying new medications for the treatment of GTD and other gynecologic tumors, including immunotherapy. And also doctors continue to evaluate different combinations of current treatment options and various drugs and integrate new approaches to surgery that are being studied in clinical trials. Researchers are learning more about what causes GTD, including possible chromosome changes or problems. So research is being done to develop more sensitive blood tests to determine hCG levels at smaller amounts. Clinical trials are underway to find better ways to reduce symptoms and side effects of the presently available eye cancer treatments to improve patients’ comfort and quality of life.

Advancement in Gestational Trophoblastic Disease Research

Doctors are learning about eyelid cancer, methods to prevent it, treat it best, and provide the best care to patients diagnosed with this cancer. 

The following research areas may include new options for patients through clinical trials. Always talk to the doctor about the diagnostic and treatment options best for you.

The following research areas may comprise new options for patients through clinical trials. Because GTD is uncommon, GTD-only clinical trials can be hard to find. However, several other clinical trials are available to people with different tumors, particularly other gynecologic tumors, including GTD. Always talk to your doctor about the best diagnostic and treatment options for you.

New drug therapies

Researchers are studying new medications for the treatment of GTD and other gynecologic tumors, including immunotherapy ​1​. Because, immunotherapy boosts the body’s natural defense to fight cancer.

New treatment combinations

Doctors continue to evaluate different combinations of current treatment options and various drugs and integrate new approaches to surgery that are being studied in clinical trials ​1​.

Causes of GTD

Researchers are learning more about what causes GTD, including possible chromosome changes or problems.

Earlier diagnosis

Research is going on to develop more sensitive blood tests to determine hCG levels at smaller amounts. This could help diagnose Gestational trophoblastic disease at an earlier stage ​2​.

Palliative care or supportive care

Clinical trials are underway to find better ways to reduce symptoms and side effects of the presently available germ cell tumor treatments to improve patients’ comfort and quality of life.

References

  1. 1.
    Clark JJ, Slater S, Seckl MJ. Treatment of gestational trophoblastic disease in the 2020s. Current Opinion in Obstetrics & Gynecology. Published online December 15, 2020:7-12. doi:10.1097/gco.0000000000000674
  2. 2.
    Dhanda S, Ramani S, Thakur M. Gestational Trophoblastic Disease: A Multimodality Imaging Approach with Impact on Diagnosis and Management. Radiology Research and Practice. Published online 2014:1-12. doi:10.1155/2014/842751