Dimethylglycine (DMG) (also known as N,N-dimethylglycine) is a derivative of the amino acid glycine .it is an amino acid that occurs naturally in plant and animal cells, as well as in a variety of foods such beans, cereal grains, and liver. It’s used to strengthen the immune system, improve vitality, and treat seizures and autism. DMG’s immune system effectiveness has been reported to be favorable. None of these claims, however, have been proven in clinical research. When one of the methyl groups in trimethyl-glycine is lost, it can be produced. It is also a byproduct of choline metabolism. Dimethylglycine has been proposed as an anti-inflammatory, immuno-stimulant, and therapy for autism, epilepsy, and mitochondrial illness.
DMG was once known as Vitamin B16, however unlike real B vitamins, a shortage of DMG in the diet has no negative consequences, and it is produced by the human body in the citric acid (or Krebs) cycle, thus it does not satisfy the criteria of a vitamin.
DMG is generated in cells as a byproduct of choline metabolism and is regarded as an antioxidant and oxygen enhancer at the cellular level. Choline and DMG levels are greater in foetal plasma than in maternal plasma. DMG levels in the blood have been shown to be lower in cystic fibrosis patients than in healthy youngsters.
It is only present in trace levels in the body and only for a few seconds at a time.
Attention deficit hyperactivity disorder (ADHD), epilepsy, chronic fatigue syndrome (CFS), allergies, respiratory diseases, pain and swelling (inflammation), cancer, alcoholism, and drug addiction are all conditions treated with dimethylglycine. It’s also utilized to help with autistic speech and behaviours, nervous system function, liver function, oxygen utilization, and sports performance. It is used by some individuals to relieve stress and the affects of ageing, as well as to strengthen the immune system’s defenses against infection.
DMG was utilized as an ester to improve the solubility and bioavailability of a cancer research prodrug , on the other hand, is not the active moiety, and there is no evidence that it possesses anticancer properties.
Dimethylglycine has been used to boost immunological function and treat autism and seizures, however the evidence is inconsistent or nonexistent.
It’s used to strengthen the immune system, improve vitality, and treat seizures and autism. DMG’s immune system effectiveness has been reported to be favorable. None of these claims, however, have been proven in clinical research.
DMG has no possible side effects if used for a short period of time, although more study is needed.