Stages of Desmoplastic Infantile Ganglioglioma Childhood Tumour

Executive Summary

The staging system of Desmoplastic Infantile Ganglioglioma (DIG), a Childhood Tumor, helps determine the tumor’s location and its metastasis. The staging system of Desmoplastic Infantile Ganglioglioma (DIG), Childhood Tumor uses diagnostic tests. A TNM staging system is used to identify the different stages of tumor. No standard staging system is available for Desmoplastic Infantile Ganglioglioma Childhood Tumor. Therefore, Desmoplastic Infantile Ganglioglioma, Childhood Tumors or DIG are usually described in their grade. Desmoplastic infantile ganglioglioma tumor growth can be classified as low-grade tumors and high-grade tumors. A low-grade tumor looks similar to the healthy, normal tissue and will possess a different cell grouping while a high-grade tumor seems significantly different from healthy normal tissue.

Desmoplastic infantile ganglioglioma childhood tumors are classified as grade I as per the World Health Organization, which shows distinct, unconnected, and unlikely to metastasize to other tissues or organs. In this grade I, the tumor growth can be successfully eliminated and treated by surgery. If the desmoplastic infantile ganglioglioma tumor recurs again in the body, another round of tests and scans would be required to learn about it and its extent.

Staging Grade of Desmoplastic infantile Ganglioglioma Childhood tumors

Staging and grading describe a disease or tumor condition in terms of gravity, location, and metastatic behavior. The doctor will use various diagnostic tests to determine the disease stages and grades of desmoplastic infantile ganglioglioma childhood tumor. Knowing the stage will help the healthcare team to understand how advanced the disease condition is and what treatment plan can be employed to treat the condition. Describing the stage and grade of a disease condition like Desmoplastic Infantile Ganglioglioma (DIG), Childhood Tumor will help predict the patient’s prognosis. Staging can be vital in determining a patient’s survival rate once being diagnosed with the disease condition.

In the case of tumours or cancerous growth, doctors usually use a TNM staging system. T stands for tumour, N stands for nodes, and M stands for metastasis in this system. 

Different tumors have different types of stage descriptions. However, in the case of Desmoplastic Infantile Ganglioglioma Childhood Tumor’s stages there is no standard staging system available. Desmoplastic Infantile Ganglioglioma, Childhood Tumors or DIG are usually described in their grade ​1​.

Grade

The grade of desmoplastic infantile ganglioglioma tumour growth describes how much the tumour cells look like normal healthy cells when examined under a microscope. The doctor will compare the tumour tissue with normal, healthy tissue. The normal tissue will consist of many different types of cells grouped. The grade of the tumour will aid the doctor in predicting its growth and ability to spread or invade other tissues or organs. In general, the lower the tumour grade, the lowest the associated risk for the patient. Such patients will have a better prognosis.  

Desmoplastic infantile ganglioglioma tumor growth can be classified as low-grade tumors and high-grade tumors. A low-grade tumor is also called a differentiated tumor. Such tumors look similar to the healthy, normal tissue and will possess a different cell grouping. A high-grade tumor, also called a poorly differentiated tumor, would look significantly different from healthy normal tissue.

The World Health Organization’s (WHO) classification system for central nervous system tumors, desmoplastic infantile ganglioglioma, childhood tumors are classified as grade I tumors. A grade I tumors is described as distinct, unconnected, unlikely to metastasise to other tissues or organs. Also, a grade I tumors means that the tumor growth can be successfully eliminated and treated by surgery ​2​

Recurrent of desmoplastic infantile ganglioglioma tumour

A recurrent tumor refers to cancer or tumor growth that comes or recurs back after treatment. If the desmoplastic infantile ganglioglioma tumor recurs once again in the body, another round of tests, scans would be required to learn about it and the extent of the recurrence.

The tests and scans conducted would be similar to those carried out during the original cancer or tumor diagnosis. 

References

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    Lönnrot K, Terho M, Kähärä V, Haapasalo H, Helén P. Desmoplastic infantile ganglioglioma: novel aspects in clinical presentation and genetics. Surgical Neurology. Published online September 2007:304-308. doi:10.1016/j.surneu.2006.11.043
  2. 2.
    Lam C, Bouffet E, Tabori U, Mabbott D, Taylor M, Bartels U. Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors. Pediatr Blood Cancer. Published online March 2010:476-479. doi:10.1002/pbc.22298