Signs and Symptoms of Chronic Myeloid Leukemia

People having CML may experience the following signs or symptoms. Or, the cause of a symptom can be another medical condition that is not leukemia. However, CML usually progresses slowly, which means symptoms may not appear for a long time. The symptoms are generally mild at first and get worse eventually with time. And often, people with CML do not have any symptoms. CML is commonly found with a blood test taken for some other reason.

  • Fever
  • Fatigue or weakness, like shortness of breath while doing everyday activities
  • Excessive sweating, especially at night
  • Weight loss
  • Bone pain
  • Itching
  • Abdominal swelling or discomfort because of enlarged spleen. This may be specifically noticeable in the upper left part of the abdomen.
  • Bleeding
  • Feeling full when you haven’t eaten much.