Executive Summary
The Childhood Germ Cell Tumour will have various symptoms and signs. The signs and symptoms of childhood germ cell tumor experienced by the individuals help describe a medical problem. Some of the common symptoms of childhood germ cell tumors include the elevated levels of alpha-fetoprotein (AFP), tumor, swelling, and also a mass that can be felt or seen. While, constipation, incontinence, and leg weakness can occur if the tumor is in the sacrum (a segment of the vertebral column that forms the top part of the pelvis), compressing structures. Besides it, the elevated levels of beta-human chorionic gonadotropin (ß-HCG), abnormal shape, or irregularity in, testicular size, shortness of breath, or wheezing if tumors in the chest are pressing on the lungs, abdominal pain, urinary retention, meaning the inability to urinate, and cough or difficulty breathing.
Signs and Symptoms of Childhood Germ Cell Tumour
A child having an extracranial, extragonadal germ cell tumor may experience the following symptoms and signs. A symptom can be something that only the person experiencing can identify and describe, such as nausea, fatigue, or pain. Whereas, a sign is something that other people can identify and see, like a rash, fever, or an elevated pulse. Altogether, signs and symptoms can help describe a medical problem. Even so, children with a germ cell tumor may not have any of the symptoms and signs described below. Or, the cause of a sign or symptom may be a medical condition that is not a tumor 1.
- Elevated levels of alpha-fetoprotein (AFP)
- A tumor, swelling, or mass that can be seen or felt
- Constipation, incontinence, and leg weakness can occur if the tumor is in the sacrum (a segment of the vertebral column that forms the top part of the pelvis), compressing structures.
- Elevated levels of beta-human chorionic gonadotropin (ß-HCG)
- Abnormal shape, or irregularity in, testicular size
- Shortness of breath or wheezing if tumors in the chest are pressing on the lungs
- Abdominal pain
- Urinary retention, meaning the inability to urinate
- Cough or difficulty breathing
References
- 1.Pierce JL, Frazier AL, Amatruda JF. Pediatric Germ Cell Tumors: A Developmental Perspective. Advances in Urology. Published online 2018:1-8. doi:10.1155/2018/9059382