Clinical Trial About Childhood Germ Cell Tumor

Executive Summary

Clinical trials are a better method for treating childhood germ cell tumor. The evaluation of new drugs, different combinations of treatments, new approaches to surgery, and new therapies are part of childhood germ cell tumor clinical trials. New treatments with better efficacy and safety are the outcome of a clinical trial. The results of the clinical trials have been effective in reducing the symptoms and side effects during the treatment. So, volunteers or patients willing to participate in the clinical trials should communicate with their doctor and research expertise. This will help them to take decision regarding participating in the problem while signing informed consent.

The volunteers willingly participate as they know the studies help advance the treatment of childhood germ cell tumor. Eligibility criteria for childhood germ cell tumor clinical trials ensure that the participants are safe, bound to no ill effects, and well-structured research. People who take part in clinical trials of childhood germ cell tumor may withdraw their participation at any moment in time due to any personal or medical conditions. It may be because the treatment is not working or giving the desired results, including severe risks and side effects.

Clinical Trials for Childhood Germ Cell Tumor

On the path to finding different ways to treat cancer, various research and trials have been carried out to find safe and effective treatments other than the standard ones. Every drug that is used now was once tested in clinical trials. The clinical studies mainly focus on finding a safe, effective, and better treatment or diagnostic procedure. therefore, they evaluate new chemotherapy or radiotherapy drugs for better treatment of cancer ​1​.

Taking part in clinical trials can benefit people by receiving treatment before it is available. As the coin has two sides, there are some risks with the clinical trials, including its side effects and the possibility of new clinical trials not working. Clinical trials are also conducted on drugs and other therapies that can relieve the symptoms and side effects of treatments like chemotherapy, radiotherapy, etc.

Participating in clinical trials can have many reasons. For some people, taking part in a clinical trial is the only option to receive the best treatment for the type of cancer. Because standard treatments are not perfect, people are willing to face the uncertainty and challenges of a clinical trial to seek a better result ​2​

Some clinical trials study new ways to relieve symptoms and side effects during treatment. Others learn ways to manage the late effects that may happen a long time after treatment. 

Insurance and the costs of clinical trials change depending upon location and by study. Some of the expenses from participating in the clinical trial are reimbursed in several programs.


Clinical trials also have specific “eligibility criteria” rules that help research patients be safe. You and your research team carefully review these criteria together. People participating in a clinical trial can stop participating at any time for any medical or personal reasons. The reasons may include that the new treatment is not working or has severe side effects. Experts keep an eye on clinical trials for any problems with each study.


  1. 1.
    Olson TA, Murray MJ, Rodriguez-Galindo C, et al. Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. JCO. Published online September 20, 2015:3018-3028. doi:10.1200/jco.2014.60.5337
  2. 2.
    Frazier AL, Hale JP, Rodriguez-Galindo C, et al. Revised Risk Classification for Pediatric Extracranial Germ Cell Tumors Based on 25 Years of Clinical Trial Data From the United Kingdom and United States. JCO. Published online January 10, 2015:195-201. doi:10.1200/jco.2014.58.3369