Clinical trials are considered a better method for treating childhood central nervous system tumor. The evaluation of new drugs, different combinations of treatments, new approaches to radiation therapy or surgery, and new therapies are integrated into central nervous system tumor clinical trials in childhood. New treatments with better efficacy and safety are the outcome of a clinical trial. The results of the clinical trials have been effective in reducing the symptoms and side effects during the treatment. Volunteers or patients willing to participate in the clinical trials should communicate with their doctor and healthcare team and research expertise to make well decided informed choices regarding participating in the problem while signing informed consent. The volunteers willingly participate as they know the studies are a way to help advance the treatment of early- and late-stage of central nervous system tumor. Some clinical trials study new ways to relieve symptoms and side effects during treatment. Others learn ways to manage the late effects that may happen a long time after Central Nervous System tumor treatment.
Clinical Trials of Childhood Central Nervous System Tumors
On the path to finding different ways to treat cancer, various research and clinical trials have been carried out to find safe and effective treatments other than the standard ones. Every drug that is used now was once tested in clinical trials. The Clinical Trials of Central Nervous System tumors studies mainly focus on finding a safe, effective, and better treatment or diagnostic procedures 1. They evaluate new chemotherapy or radiotherapy drugs for better treatment of cancer.
Taking part in clinical trials of Central Nervous System tumors can benefit people by receiving treatment before it is available 2. As the coin has two sides, there are some risks with the clinical trials, including its side effects and the possibility of new clinical trials not working. Clinical trials are also conducted on drugs and other therapies that can relieve the symptoms and side effects of treatments like chemotherapy, radiotherapy, etc. People are strongly encouraged to talk with their health care team about the pros and cons of joining a specific study.
Participating in clinical trials can have many reasons. For some people, taking part in a clinical trial is the only left out option to receive the best treatment for the Central Nervous System tumors. Because standard treatments are not perfect, people are willing to face the uncertainty and challenges of a clinical trial to seek a better result.
Some clinical trials study new ways to relieve symptoms and side effects during treatment. Others learn ways to manage the late effects that may happen a long time after Central Nervous System tumor treatment.
Insurance and the costs of clinical trials of Central Nervous System tumors change depending upon location and by study. Some of the expenses from participating in the clinical trial are reimbursed in several programs.
Clinical trials of Central Nervous System tumors also have specific “eligibility criteria” rules that help research patients be safe. You and your research team carefully review these criteria together. People participating in a clinical trial can stop participating at any time for any medical or personal reasons. The reasons may include that the new treatment is not working or has severe side effects. Experts keep an eye on clinical trials for any problems with each study.
- 1.Hargrave DR, Zacharoulis S. Pediatric CNS tumors: current treatment and future directions. Expert Review of Neurotherapeutics. Published online August 2007:1029-1042. doi:10.1586/14737184.108.40.2069
- 2.Harrup R, White VM, Coory M, et al. Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study. Journal of Adolescent and Young Adult Oncology. Published online April 1, 2021:202-208. doi:10.1089/jayao.2020.0074