Glucarpidase: A Breakthrough Treatment for High-Dose Methotrexate Toxicity in Cancer

US Brand Name for Glucarpidase(s): Voraxaze

Use in Cancer Treatment

Glucarpidase is to treat the following conditions:

Methotrexate, an anticancer medication, has toxic blood levels. In adults and children whose kidneys aren’t performing properly, it helps to eliminate methotrexate from the body.

For definition and related information- Definition from the NCI Drug Dictionary 

Glucarpidase Facts on MedlinePlus

A layman’s overview of key information about this medication, which may include:

A summary of key facts regarding this medication in layman’s terms, which may contain the following:

  • Cautions about this medicine
  • What is the use and how?
  • Whom should you consult before taking it?
  • What you should know about it before using it?
  • Other drugs that might interact with it
  • Possible negative effects

Glucarpidase Drugs are frequently under research to see whether they can assist treat or prevent conditions other than those already prevalent. This patient information leaflet covers uses which have been under authorization. Much of the material, though, might also apply to authorized uses that are being investigated.