Filgrastim: A Medication Used to Increase White Blood Cells in Cancer Patients

US Brand Name(s): Granix, Neupogen, Nivestym, Zarxio

Use in Cancer Treatment

Filgrastim has been authorized to lower the risk of infection in individuals with the following conditions:

Neutropenia is a side effect of various kinds of chemotherapy, such as:

  • Acute myeloid leukemia is treated with chemotherapy.
  • In individuals with non-myeloid cancer, myeloablative chemotherapy is used before a bone marrow transplant.
  • In patients with non-myeloid cancer, myelosuppressive chemotherapy is used.
  • Filgrastim has also been allowed to aid in the movement of stem cells from the bone marrow to the circulation, where they may be collected, preserved, and subsequently returned to the patient in the case of autologous stem cell transplantation.
  • Filgrastim is also authorized for the treatment of neutropenia not induced by cancer therapy.

Pegfilgrastim is a kind of filgrastim that is available in a different form. See the Pegfilgrastim Drug Information Summary for further details.

Detailed scientific definition- Definition from the NCI Drug Dictionary 

 Filgrastim Facts on MedlinePlus – A summary of key information about this medication in layman’s terms, which may contain the following:

cautions about this medicine, what it’s used for and how it’s used, what you should tell your doctor before taking it, what you should know about it before using it, other drugs that might interact with it, and possible negative effects

Drugs are frequently investigated to see whether they can assist treat or prevent conditions other than those for which they have been authorized. Only authorized uses of the medication are covered by this patient information leaflet. Much of the material, though, might also apply to authorized uses that are being investigated.