Use of Apalutamide in Cancer Treatment

Brand name: Erleada

Use of Apalutamide in Cancer Treatment

Apalutamide authorizes to treat the following conditions:

Prostate cancer is a disease that affects men.

  • Patients with cancer that has metastasized (spread to other regions of the body) and is castration-resistant (has responded to treatments that lower testosterone levels).
  • Patients with non-metastatic cancer who are castration-resistant (has not responded to treatments that lower testosterone levels).


A tiny chemical and androgen receptor (AR) antagonist with anticancer potential. In fact, Apalutamide binds to AR in target tissues, inhibiting androgen-induced receptor activation and allowing inactive complexes to form that can’t be translocated to the nucleus. This inhibits AR-responsive genes from binding to and its transcription. This, in turn, suppresses the production of genes that control prostate cancer cell proliferation, potentially halting cell growth in AR-expressing tumor cells.

Apalutamide  Information on MedlinePlus – A summary of key information regarding this medication in layman’s terms, which may contain the following:

Cautions about this medicine; what it’s used for and how it’s used; what you should tell your doctor before taking it; things you should know about it before using it; other drugs that might interact with it; and possible negative effects

Experts frequently investigate drugs to see whether they can assist treat or prevent conditions other than those for which they have an authorization. Only authorized uses of the medication are covered by this patient information leaflet. Much of the material, though, might also apply to authorization of its uses that are under investigatigation.