Clinical trials is a better method for treating breast cancer. Clinical trials of breast cancer evaluates new drugs, different combinations of treatments, new approaches to radiation therapy or surgery, and new therapies. Almost 4,444 individuals participate in clinical trials. They aims to be the first ones to receive treatment before revealing it to the public. Clinical trials are used for all four stages of breast cancer.
New treatments with better efficacy and safety are the outcome of a clinical trial. The results of the clinical trials reduces the symptoms and side effects during the treatment. Volunteers or patients willingly participate in the clinical trials. They communicate with their doctor, healthcare team, and research expertise. It makes well decided informed choices regarding participating in the problem. Participants signs the informed consent.
The volunteers willingly participate as they know the studies help in advancing the treatment of early- and late-stage breast cancer in situ. The benefits of clinical trials include using high-dose chemotherapy. The other benefits includes delivery of the drug more frequently than the traditional 3-week interval. Adding trastuzumab for early breast cancer are tested and confirmed in clinical trials.
Clinical Trials for Breast Cancer
Doctors and scientists are always looking for better ways to care for people with breast cancer. Doctors design research with volunteers called clinical study to make scientific progress. Clinical trials are the best option for treating breast cancer. Many people focus on new treatments to see if they are safe, effective, and superior to existing ones. These studies evaluate new drugs, different combinations of treatments, new approaches to radiation therapy or surgery, and new treatments.
Individual participating in clinical trial:
Around 4,444 people are participating in clinical trials. These may be the first ones to receive treatment before revealing it to the public 1. However, clinical trials carry some risks. Possible side effects may occur and the possibility that new treatments may not work are some major risks.
People talk to their health team about the pros and cons of participating in a particular study. Several clinical studies are investigating new ways to reduce symptoms and side effects during treatment. Others are looking for ways to treat long-term sequelae that can occur long after treatment. Talk to your doctor about clinical trials for symptoms and side effects.
Deciding to participate in a clinical trial
People choose to participate in a clinical trial for many reasons. Clinical trial is the best treatment option available for some people because no standard treatment is perfect. People who prepare to face the uncertainty of a clinical trial is hoping for a better outcome. Others volunteer participate in clinical trials because they know the studies help in advancing the treatment of early- and late-stage breast cancer in situ. Even if people don’t directly benefit from a clinical trial, their participation could benefit future breast cancer patients.
For example, the benefits of using high-dose chemotherapy, delivering the drug more frequently than the traditional 3-week interval, and the adding trastuzumab for early breast cancer are tested and confirmed in clinical trials.
Coverage and costs
Coverage and costs for clinical trials varies according to location and study. Some of the expenses associated with participating in a clinical trial are reimbursed in some programs. In others, they are not reimbursed. First, you must discuss how your treatment in a clinical trial is covered with the research team and your insurance company. Learn more about clinical trial health coverage.
Sometimes people worry that they won’t get any treatment in a clinical trial by taking a placebo or a “sugar pill”. Breast cancer trials never uses a placebo instead of standard therapy. You usually get a new or standard treatment in a breast cancer clinical trial. So even if you don’t get a new drug or other new medicine, your breast cancer will be treated the same way as if you are not in the trial. Sometimes you can get the standard treatment plus a placebo instead of standard treatment plus the new study treatment. Study participants are always informed when a placebo is used.
Also Read: Stages and types of Breast cancer
Patient safety and informed consent
Everyone must sign an informed consent to participate in a clinal trial. A physician must describe all treatment options to understand how the standard treatment and new treatment differ from each other while giving informed consent. List all risks of the new treatment, which may or may not be different from the dangers of the standard treatment. Explain what each person will require to participate in a clinical trial, including the number of doctor visits, tests, and treatment schedules.
Clinical trials have specific “eligibility criteria” rules that help structure the study and ensure patient safety 2. Together you and the research team carefully review these criteria.
Clinical trial participants can stop participating for personal or medical reasons. If a new treatment doesn’t work or if there are serious side effects, participate can withdraw from the clinical trial. These trials are closely monitored by experts who oversee any problems with each study.
People in clinical trials discuss with their doctors and researchers regarding the treatment and care during and after the clinical trials. The time when clinical trial ends and whether participants choose to leave the clinical trial before it ends is also important to know.
- 1.Kuerer H, van la. Breast Cancer Clinical Trials: Past Half Century Moving Forward Advancing Patient Outcomes. Ann Surg Oncol. 2016;23(10):3145-3152. doi:10.1245/s10434-016-5326-9
- 2.Batra A, Kong S, Cheung W. Eligibility of real-world patients with metastatic breast cancer for clinical trials. Breast. 2020;54:171-178. doi:10.1016/j.breast.2020.10.005