Statistics of Cholangiocarcinoma

Executive Summary

Cholangiocarcinoma is the rare cancer type prevalent in the US region, with 2000-3000 new cases diagnosed every year. The prevalence ranges from 0.01%-0.46%. The breakout of chronic parasite infestation resulted in a higher majority of Cholangiocarcinoma in Asia. Compared to women, most men suffer from Cholangiocarcinoma, mainly among older adults. Almost 30% of the population is affected by primary sclerosing cholangitis. The incidence of intrahepatic Cholangiocarcinoma has steadily risen in North America, Europe, Asia, and Australia. The cases of Cholangiocarcinoma are rising, and the reason is still not known. The prevalence of putative cholangiocarcinoma risk factors, including HIV infection, increased throughout this period.

What is the Statistics of Cholangiocarcinoma?

Based on Statistics on, Cholangiocarcinoma is a relatively rare cancer; in the United States, between 2,000 and 3,000 new cases are diagnosed each year, resulting in an annual incidence of 1–2 cases per 100,000. According to autopsy studies, the prevalence ranges from 0.01 per cent to 0.46 per cent ​1​.

Due to widespread chronic parasite infestation, Asia has a greater prevalence of cholangiocarcinoma. Cholangiocarcinoma is more common as people get older. Men are slightly more likely than women to develop the condition (possibly due to the higher rate of primary sclerosing cholangitis, a significant risk factor).

Also Read: Mind-body approaches.

According to research, developing cholangiocarcinoma in persons with primary sclerosing cholangitis is as high as 30%. Multiple studies have shown that intrahepatic cholangiocarcinoma has been steadily rising in North America, Europe, Asia, and Australia.

The causes for the rise in cholangiocarcinoma cases are unknown based on Statistics of Cholangiocarcinoma; new diagnostic technologies may be partly to blame, but the prevalence of putative cholangiocarcinoma risk factors, such as HIV infection, has also risen throughout this period ​2​.


  1. 1.
    Patel N, Benipal B. Incidence of Cholangiocarcinoma in the USA from 2001 to 2015: A US Cancer Statistics Analysis of 50 States. Cureus. Published online January 25, 2019. doi:10.7759/cureus.3962
  2. 2.
    Kirstein MM, Vogel A. Epidemiology and Risk Factors of Cholangiocarcinoma. Visc Med. Published online 2016:395-400. doi:10.1159/000453013