Sign and Symptoms of Acute Myeloid Leukemia

Executive Summary

Acute myeloid leukemia is diagnosed based on its symptoms. The signs and symptoms of the AML experienced by the individuals help describe a medical problem. The most common symptoms of acute myeloid leukemia include fatigue, weakness, pale skin, fever, bone, back or abdominal pain, weight loss, frequent infections, easy bleeding or bruising that does not stop easily, swollen lymph nodes or glands, difficulty breathing or shortness of breath, unusual long menstrual cycle for women, chest pain, dizziness, red, pin-head sized spots on the skin, headache, swollen or bleeding gums, skin nodules, blurred vision, and wounds or sores that don’t go away.

Signs and Symptoms of Acute Myeloid Leukemia

People having Acute myeloid leukaemia may experience the following symptoms or signs ​1​. Sometimes, people with AML do not have any of these symptoms. Or, the cause of a symptom can be a different medical condition that is not leukaemia.

  • Fatigue
  • Weakness
  • Pale skin
  • Fever
  • Bone, back, or abdominal pain
  • Weight loss
  • Frequent infections or infections that don’t go away
  • Easy bleeding or bruising that does not stop easily
  • Swollen lymph nodes or glands
  • Difficulty breathing or shortness of breath
  • Unusually long menstrual cycle for women
  • Chest pain
  • Dizziness
  • Red, pin-head sized spots on the skin
  • Headache
  • Swollen or bleeding gums
  • Skin nodules
  • Blurred vision
  • Wounds or sores that don’t go away


  1. 1.
    Albrecht TA. Physiologic and Psychological Symptoms Experienced by Adults With Acute Leukemia: An Integrative Literature Review. Oncology Nursing Forum. Published online April 25, 2014:286-295. doi:10.1188/14.onf.286-295