Sign and Symptoms of Acute Myeloid Leukemia

Executive Summary

Acute myeloid leukemia, to begin with, is diagnosed based on its symptoms. And so the signs and symptoms of the AML experienced by the individuals help describe a medical condition. There are various common symptoms of acute myeloid leukemia such as fatigue, weakness, pale skin, fever, bone, back or abdominal pain, weight loss, frequent infections, and bleeding or bruising that does not stop easily. The patient might also experience swollen lymph nodes or glands, difficulty breathing or shortness of breath, chest pain, dizziness, red, pin-head sized spots on the skin, headache, swollen or bleeding gums, skin nodules, and blurred vision.

Signs and Symptoms of Acute Myeloid Leukemia

People having Acute myeloid leukemia may experience the following symptoms or signs ​1​. However, there are times when, people with AML may not have any of these symptoms. Or, the cause of a symptom can be a different medical condition that is not leukemia.

  • Fatigue
  • Weakness
  • Pale skin
  • Fever
  • Bone, back, or abdominal pain
  • Weight loss
  • Frequent infections or infections that don’t go away
  • Easy bleeding or bruising that does not stop easily
  • Swollen lymph nodes or glands
  • Difficulty breathing or shortness of breath
  • Unusually long menstrual cycle for women
  • Chest pain
  • Dizziness
  • Red, pin-head sized spots on the skin
  • Headache
  • Swollen or bleeding gums
  • Skin nodules
  • Blurred vision
  • Wounds or sores that don’t go away


  1. 1.
    Albrecht TA. Physiologic and Psychological Symptoms Experienced by Adults With Acute Leukemia: An Integrative Literature Review. Oncology Nursing Forum. Published online April 25, 2014:286-295. doi:10.1188/14.onf.286-295