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Book Appointment with Dr Deepika Nayak in Mumbai

Dr Deepika Nayak

Surgical Oncologist

12 Years Exp. Mumbai

Gynecological Cancer

HCG Cancer Centre, Mumbai

12 years of experience

MBBS, MS - General Surgery, MCh - Surgical Oncology

Mumbai

About Dr Deepika Nayak:

Dr Deepika Nayak is a Surgical Oncologist at HCG Cancer Centre, Borivali, Mumbai. Dr Deepika Nayak completed her MBBS from a renowned medical college in Karnataka. She did her Masters in General Surgery from a renowned medical college in Kerala. Further, she went on to complete her MCh from one of India's premier institutes in Chennai, India. Her area of interest is Surgical Oncology as a whole. She has many publications in national and international journals to her credit.

Education:

MBBS - Manipal Academy Of Higher Education, Manipal, India, 2008 MS - General Surgery - University of kerela, 2010 MCh - Surgical Oncology - The Tamil Nadu Dr. M.G.R. Medical University (TNMGRMU), 2014

Experience:

Consutant at HCG Cancer Center,Mumbai

Areas of interest:

Gynecological Cancer, Gastrointestinal (GI) Cancer, Genitourinary Cancer, Head And Neck Cancer.

Research publications:

Siddharth, Sumit & Nayak, Deepika & Nayak, Anmada & Das, Sarita & Kundu, Chanakya. (2016). ABT-888 and Quinacrine induced apoptosis in metastatic breast cancer stem cells by inhibiting base excision repair via Adenomatous polyposis coli. DNA Repair. 45. https://doi.org/10.1016/j.dnarep.2016.05.034 Siddharth, Sumit & Nayak, Anmada & Nayak, Deepika & Bindhani, B.K. & Kundu, Chanakya. (2017). Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA-nanoparticles caused apoptosis in doxorubicin resistance breast cancer cells through induction of DNA damage. Scientific Reports. 7. https://doi.org/10.1038/s41598-017-02134-z Siddharth, Sumit & Goutam, Kunal & Das, Sarita & Nayak, Anmada & Nayak, Deepika & Sethy, Chinmayee & Wyatt, Michael & Kundu, Chanakya. (2017). Nectin-4 is a breast cancer stem cell marker that induces WNT/_-Catenin signaling via Pi3k/Akt axis. The International Journal of Biochemistry & Cell Biology. 89. https://doi.org/10.1016/j.biocel.2017.06.007 Nayak, Anmada & Siddharth, Sumit & Das, Sarita & Nayak, Deepika & Sethy, Chinmayee & Kundu, Chanakya. (2017). Nanoquinacrine caused apoptosis in oral cancer stem cells by disrupting the interaction between GLI1 and _ catenin through activation of GSK3_. Toxicology and Applied Pharmacology. 330. https://doi.org/10.1016/j.taap.2017.07.008 Das, Sarita & Tripathi, Neha & Siddharth, Sumit & Nayak, Anmada & Nayak, Deepika & Sethy, Chinmayee & Bharatam, Prasad & Kundu, Chanakya. (2017). Etoposide and doxorubicin enhance the sensitivity of triple negative breast cancers through modulation of TRAIL-DR5 axis. Apoptosis. 22. https://doi.org/10.1007/s10495-017-1400-4 Das, Sarita & Nayak, Anmada & Siddharth, Sumit & Nayak, Deepika & Narayan, Satya & Kundu, Chanakya. (2017). TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions. Cellular Oncology. 40. https://doi.org/10.1007/s13402-017-0347-3 Satapathy, Shakti & Nayak, Anmada & Siddharth, Sumit & Das, Sarita & Nayak, Deepika & Kundu, Chanakya. (2018). Metallic gold and bioactive Quinacrine hybrid nanoparticles inhibit oral cancer stem cell and angiogenesis by deregulating inflammatory cytokines in p53 dependent manner. Nanomedicine : nanotechnology, biology, and medicine. 14. https://doi.org/10.1016/j.nano.2018.01.007 Panda, Pravati & Nayak, Sabita & Sahoo, Susanta & Mohapatra, Seetaram & Nayak, Deepika & Pradhan, Rajalaxmi & Kundu, Chanakya. (2018). Diastereoselective synthesis of novel spiro indanone fused pyrano[3,2- c ]chromene derivatives following hetero-DielsРAlder reaction and in vitro anticancer studies. RSC Advances. 8. 16802-16814. https://doi.org/10.1039/C8RA02729C Siddharth, Sumit & Nayak, Anmada & Das, Sarita & Nayak, Deepika & Panda, Jyochanamayi & Wyatt, Michael & Kundu, Chanakya. (2018). The soluble Nectin-4 ecto-domain promotes breast cancer induced angiogenesis via endothelial Integrin-_4. The International Journal of Biochemistry & Cell Biology. 102. https://doi.org/10.1016/j.biocel.2018.07.011 Sethy, Chinmayee & Goutam, Kunal & Nayak, Deepika & Pradhan, Rajalaxmi & Bitew, Sefinew Molla & Chatterjee, Subhajit & Rout, Niranjan & Wyatt, Michael & Narayan, Satya & Kundu, Chanakya. (2018). Clinical Significance of Nectin-4 Expression in Metastasis and Angiogenesis for Tumor Relapse. https://doi.org/10.20944/preprints201810.0154.v1 Magar, Shital & Nayak, Deepika & Mahajan, Umesh & Patil, Kalpesh & Shinde, Sachin & Goyal, Sameer & Swaminarayan, Shivang & Patil, C. & Ojha, Shreesh & Kundu, Chanakya. (2018). Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats. Scientific Reports. 8. https://doi.org/10.1038/s41598-018-31971-9 Nayak, Anmada & Das, Sarita & Nayak, Deepika & Sethy, Chinmayee & Narayan, Satya & Kundu, Chanakya. (2019). Nanoquinacrine sensitizes 5-FU-resistant cervical cancer stem-like cells by down-regulating Nectin-4 via ADAM-17 mediated NOTCH deregulation. Cellular Oncology. 42. 1-15. https://doi.org/10.1007/s13402-018-0417-1 Hembram, Krushna & Chatterjee, Subhajit & Sethy, Chinmayee & Nayak, Deepika & Pradhan, Rajalaxmi & Bitew, Sefinew Molla & Bindhani, B.K. & Kundu, Chanakya. (2019). A comparative and mechanistic study on the anti-cancer activity of quinacrine based silver and gold hybrid nanoparticles in head and neck cancer. Molecular Pharmaceutics. 16. https://doi.org/10.1021/acs.molpharmaceut.9b00242 Magar, Shital & Nayak, Deepika & Mahajan, Umesh & Patil, Kalpesh & Shinde, Sachin & Goyal, Sameer & Swaminarayan, Shivang & Patil, Chandragouda & Ojha, Shreesh & Kundu, Chanakya. (2019). Retraction Note: Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats. Scientific Reports. 9. 8641. https://doi.org/10.1038/s41598-019-44557-w Sethy, Chinmayee & Goutam, Kunal & Nayak, Deepika & Pradhan, Rajalaxmi & Bitew, Sefinew Molla & Chatterjee, Subhajit & Rout, Niranjan & Wyatt, Michael & Narayan, Satya & Kundu, Chanakya. (2019). Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse. Journal of Cancer Research and Clinical Oncology. 146. https://doi.org/10.1007/s00432-019-03055-2 Bitew, Sefinew Molla & Hembram, Krushna & Chatterjee, Subhajit & Nayak, Deepika & Sethy, Chinmayee & Pradhan, Rajalaxmi & Kundu, Chanakya. (2019). PARP inhibitor Olaparib Enhances the Apoptotic Potentiality of Curcumin by Increasing the DNA Damage in Oral Cancer Cells through Inhibition of BER Cascade. Pathology & Oncology Research. 26. https://doi.org/10.1007/s12253-019-00768-0 Nayak, Deepika & Tripathi, Neha & Kathuria, Deepika & Siddharth, Sumit & Nayak, Anmada & Bharatam, Prasad & Kundu, Chanakya. (2019). Quinacrine and Curcumin synergistically increased the breast cancer stem cells death by inhibiting ABCG2 and modulating DNA damage repair pathway. The International Journal of Biochemistry & Cell Biology. 119. 105682. https://doi.org/10.1016/j.biocel.2019.105682 Hembram, Krushna & Chatterjee, Subhajit & Sethy, Chinmayee & Nayak, Deepika & Pradhan, Rajalaxmi & Bitew, Sefinew Molla & Bindhani, B.K. & Kundu, Chanakya. (2020). Correction to ТComparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck CancerУ. Molecular Pharmaceutics. XXXX. https://doi.org/10.1021/acs.molpharmaceut.0c00716

Specialisation

Gynecological Cancer, Gastrointestinal (GI) Cancer, Genitourinary Cancer, Head And Neck Cancer.